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pentobarbital will lessen the extent or effect of alprazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will reduce the extent or effect of nisoldipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.Keep an eye on Intently (one)pentobarbital will decrease the le